Faculty

Oietro De Camilli
Stephen Strittmatter  
Ira Mellman  

New center to focus on neuroscience and brain disorders

The School of Medicine has launched a new interdepartmental program, Cellular Neuroscience, Neurodegeneration and Repair (CNNR), to be led by Pietro de Camilli, M.D., FW ’79, the Eugene Higgins Professor of Cell Biology, and Stephen M. Strittmatter, M.D., Ph.D., the Vincent Coates Professor of Neurology and professor of neurobiology.

The CNNR will build on Yale’s tradition of excellence in the neurosciences through the departments of neurobiology, molecular and cellular physiology, pharmacology, cell biology, psychiatry, neurosurgery, neurology and others, and the Child Study Center. Its goal is to foster cutting-edge basic research in cellular and molecular neuroscience, promote research on neurodegeneration and repair, translate scientific insights into therapeutic strategies to prevent or delay neuronal loss, and facilitate neural repair and restoration of function. This interdisciplinary program could have a significant impact on diseases such as Alzheimer’s and Parkinson’s, amyotrophic lateral sclerosis and multiple sclerosis, as well as diseases related to polyglutamine expansion, such as Huntington’s.

De Camilli’s pioneering work on synaptic vesicles, the intracellular packets that deliver neurotransmitters into the synapse, could advance the understanding of brain function, as well as the causes of Alzheimer’s, Parkinson’s and other diseases.

Strittmatter’s identification of Nogo, a protein that blocks the regeneration of axons, has opened promising avenues in the search for therapies to repair the adult nervous system after injury, and has given new hope to those who suffer from spinal cord injuries, stroke and neurodegenerative disorders such as Alzheimer’s.

De Camilli and Strittmatter, who will retain their appointments in cell biology and neurology, respectively, will recruit up to seven new scientists for the CNNR. The searches will be carried out in collaboration with colleagues in the basic-science and clinical departments who work in the neurosciences, and the new recruits will have primary appointments in existing departments. In addition, the CNNR will provide a scientific home for more than 100 neuroscientists who now work across the Yale campus, sparking greater interactions and enhancing the scientific environment.



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European group elects cell biologist as foreign member

Ira Mellman, Ph.D. ’78, chair and Sterling Professor of Cell Biology, is one of three American scientists elected as foreign members of the European Molecular Biology Organization (EMBO) at its annual meeting in Warsaw, Poland, last October. EMBO membership is a lifelong honor, and scientists are elected on the basis of proven excellence in research. Among its members are some of Europe’s leading researchers, including 38 Nobel laureates. EMBO was established in 1964 to create a central molecular biology laboratory and a network that would enhance interactions among European laboratories. Currently there are more than 1,200 EMBO members in Europe, and only 100 investigators out-side of Europe have been named as associate members.

“It is a real honor to be one of the very few U.S. scientists to be recognized by our most distinguished European colleagues by election to EMBO membership,” said Mellman. “Science is truly an international endeavor, and I certainly plan to use this connection to further scientific exchange at all levels.”

Mellman uses a combination of biochemical, genetic and imaging methods to understand complex functions of cell biology. His work has revealed basic biological mechanisms that regulate immune responses, particularly how dendritic cells initiate and control all antigen-specific immune responses. Another area of his research involves cell polarity and asymmetry and the molecular mechanisms that sort, target and transport cell membrane components to appropriate membrane locations in different types of cells.

Mellman joined the Yale faculty in 1981 after completing his undergraduate training at Oberlin College, receiving his doctorate in human genetics from Yale in 1978 and beginning his academic career at Rockefeller University. From 1997 to 2001 he served as founding director of the Combined Graduate Program in Biological and Biomedical Sciences.

Mellman, who holds a joint appointment in the Department of Immunobiology, is an affiliate member of the Ludwig Institute for Cancer Research. He was named scientific director of the Yale Comprehensive Cancer Center in 2004. He is a fellow of the American Academy of Arts and Sciences and the Leukemia & Lymphoma Society, and he has received a Swebilius Award, the President’s Research Development Award (Leukemia & Lymphoma Society) and the Yale Science and Engineering Society Medal.


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Notes

   
           

Margaret Bia

Margaret Bia

 

 

Margaret J. Bia, M.D., professor of medicine, received the George F. Thornton Award at the annual meeting of the Connecticut chapter of the American College of Physicians in October. The award is given annually for outstanding contributions to medical education.


Linda K. Bockenstedt, M.D., the Harold W. Jockers Associate Professor of Medicine, has been named director for professional development and equity at the medical school. In this new position Bockenstedt will be responsible for creating programs to support the academic development of all faculty members and to encourage the growth of a diverse faculty body at the school. A special focus will be on the needs of women and underrepresented minorities.

 
 

 

 

 

 

Rosemarie L. Fisher, M.D., HS ’75, associate dean for graduate medical education, has won the 2006 Courage to Lead Award from the Accreditation Council for Graduate Medical Education. The award honors designated institutional officials who have demonstrated excellence in overseeing residency programs at their sponsoring institutions. Designated institutional officials are responsible for all graduate medical education programs in a teaching hospital, community hospital or other type of institution that sponsors residency programs. Fisher oversees residency programs at Yale-New Haven Hospital.

 

Rosemarie Fisher

Rosemarie Fisher

 

 

 

 

Nora Groce

Nora Groce

Nora E. Groce, Ph.D., associate professor of public health (global health) and anthropology, chaired UNICEF’s Thematic Group on Violence Against Disabled Children, which in November issued a report that is part of a larger report on violence against children. The study is a collaborative effort by the United Nations Secretary General’s Office, the World Health Organization and UNICEF and is a follow-up to a 1999 U.N. study on children and armed conflict. The new report is intended to bring the issue of violence against children to the attention of policy-makers, governments and civil society around the globe. Corrie E. Paeglow, a graduate student in the Global Health Division at the School of Public Health, served as research associate on the project.

 

 

 

Sharon L. Kagan, D.Ed., professor (adjunct) in the Child Study Center, has become the first woman to win three of the nation’s most prestigious education awards. Kagan, a leader in early childhood education, won the 2005 Harold W. McGraw Jr. Prize in Education, the 2005 James Bryant Conant Award from the Education Commission of the States and the 2004 Distinguished Service Award from the Council of Chief State School Officers.

 

 

Zeev Kain

Zeev Kain

Zeev N. Kain, M.D., M.B.A., HS ’92, FW ’93, professor of anesthesiology, pediatrics and child psychiatry and vice chair of anesthesiology, has been appointed to the editorial board of the Journal of Pediatric Psychology, the first anesthesiologist to hold this honor. Kain, who is also a member of the editorial boards of Anesthesiology and Pediatrics, is an international expert in the area of perioperative behavioral and physiological stress.

 

Each year the graduating class honors its teacher of the year with the Francis Gilman Blake Award, but this year the other three classes chose their own teachers of the year. The Class of 2006 honored Laura R. Ment, M.D., professor of pediatrics and neurology, and I. George Miller, M.D., the John F. Enders Professor of Pediatrics and professor of epidemiology and of molecular biophysics and biochemistry. The Class of 2007 selected Margaret J. Bia, M.D., professor of medicine, and the Class of 2008 named James D. Jamieson, M.D., Ph.D., professor of cell biology and biology, and Shanta E. Kapadia, M.D., lecturer in surgery (gross anatomy).

 

 

 

 

 

 

 

 

 

Jennifer P. Ruger, Ph.D., M.Sc., assistant professor in the Global Health Division of the Department of Epidemiology and Public Health, was awarded the 2005 Labelle Lectureship in Health Services Research, given annually by McMaster University in Ontario, Canada. The lectureship is given to a young investigator who has a background in health economics and research that spans disciplines, and who challenges existing methods or accepted ideas in the health services community. Ruger’s lecture, “Health and Global Governance: What’s Justice Got to Do With It?,” was presented on October 19.

 

 

Christopher van Dyck

Christopher van Dyck

 

 

Christopher H. van Dyck, M.D., FW ’91, associate professor of psychiatry and neurobiology and director of the Alzheimer’s Research Unit at the School of Medicine, was among six honorees at the “Removing the Mask” gala celebration held in October at the Omni New Haven Hotel. The mask motif is a metaphor for the devastating loss of identity and cognition caused by Alzheimer’s disease. Gov. M. Jodi Rell was the event’s honorary chair.

 

 

Agnes Vignery

Agnès Vignery

 

 

Agnès M. Vignery, Ph.D., D.D.S., associate professor of orthopaedics and rehabilitation, has been named Yale-Pfizer Global Discovery Visiting Professor for 2005. Vignery, whose research focuses on the developmental and reconstructive processes of bone, will serve as a consultant at Pfizer’s Groton (Conn.) laboratories. She will conduct collaborative research while gaining practical knowledge of the drug discovery and development process through interactions with the project teams. The program, which offers a 12-week position for one Yale faculty member to consult and do research on-site at Pfizer Global Research and Development, strengthens Yale-Pfizer alliances and provides Yale faculty with new collaborations and a better understanding of the pharmaceutical industry.

 

 
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Originally published in Yale Medicine, Spring 2006.
Copyright © 2006 Yale University School of Medicine. All rights reserved.