Richard A Flavell PhD, FRS

Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute; Department Chair, Immunobiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology

Office of Student ResearchStem Cell Center, Yale: Stem Cell Niche and Homing; Stem Cell Self-Renewal and Cell SymmetryCancer ImmunologyVascular Biology and Therapeutics ProgramImmunobiology: Lymphocyte Development; HTIPrincipal InvestigatorParasitology ProgramSkin Diseases Research Center, Yale | SPORE in Skin CancerFellowship Training | Diabetes Research CenterNIH T32 ProgramImmunology and Immunotherapy


Dr. Flavell is Sterling Professor of Immunobiology at Yale University School of Medicine, and an Investigator of the Howard Hughes Medical Institute. He received his B.Sc. (Honors) in 1967 and Ph.D. in 1970 in biochemistry from the University of Hull, England, and performed postdoctoral work in Amsterdam (1970-72) with Piet Borst and in Zurich (1972-73) with Charles Weissmann. Before accepting his current position in 1988, Dr. Flavell was first Assistant Professor (equivalent) at the University of Amsterdam (1974-79); then Head of the Laboratory of Gene Structure and Expression at the National Institute for Medical Research, Mill Hill, London (1979-82); and subsequently President and Chief Scientific Officer of Biogen Research Corporation, Cambridge, Massachusetts (1982-88). Dr. Flavell is a fellow of the Royal Society, a member of the National Academy of Sciences as well as the Institute of Medicine. Richard Flavell uses transgenic and gene-targeted mice to study Innate and Adaptive immunity, T cell tolerance and activation in immunity and autoimmunity,apoptosis, and regulation of T cell differentiation.


  • Ph.D., Hull University , 1970

Selected Publication

  • Palm NW, de Zoete MR, Cullen TW, Barry NA, Stefanowski J, Hao L, Degnan PH, Hu J, Peter I, Zhang W, Ruggiero E, Cho JH, Goodman AL and Flavell RA: Immunoglobulin a coating identifies colitogenic bacteria in inflammatory bowel disease. Cell. 2014 Aug 28;158 (5) :1000-10. PMID: 25171403

Latest Honor and Recognition

  • The Vilcek Prize in Biomedical Science(2013) , Vilcek Foundatioin
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