Michael J Caplan PhD, MD
C. N. H. Long Professor of Cellular and Molecular Physiology and Professor of Cell Biology; Chair, Cellular and Molecular Physiology

Departments & Organizations
Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and PhysiologyCell Biology
Cellular & Molecular Physiology: Membrane Proteins - Pumps and Transporters | Membrane Protein Sorting and Trafficking | Epithelial Transport of Ions and Solutes | Organ Physiology | Physiology of Human Disease | Graduate Program in Cellular and Molecular Physiology
Liver Center
Biography
Michael J. Caplan received his bachelors degree from Harvard University and his M.D. and Ph.D. degrees from Yale University in 1987. He joined Yale's Department of Cellular and Molecular Physiology as a faculty member in 1988, and is currently the C.N.H. Long Professor of Cellular and Molecular Physiology and Cell Biology.He has received fellowships from the Helen Hay Whitney Foundation, the David and Lucille Packard Foundation for Science and Engineering, and a National Young Investigator Award from the National Science Foundation. He has also received the Young Investigator Awards from the American Physiological Society and the American Society of Nephrologists.
His work focuses on understanding the ways in which kidney cells organize and maintain their unique structures. His laboratory also studies the mechanisms responsible for Autosomal Dominant Polycystic Kidney Disease, and is working to identify targets for new therapies.
Education
- M.D., Yale University , 1987
- Ph.D., Yale University , 1987
Selected Publication
- Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ. Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. J Biol Chem, 278:36786-36793, 2003.
Latest Honor and Recognition
- Charles W. Bohmfalk Teaching Prize, Yale School of Medicine
Articles
Fall 2000 | Winter 2001
Yale’s M.D./Ph.D. Program celebrates a birthday and 188 promising careers
When Donald E. Ingber graduated from Yale College in 1977, he had definite ideas about what he wanted to do in life. He...
Fall 2000 | Winter 2001
For a group of first-year students, an intense week in the lab
Exposure to some of the best minds in science has long been a benefit of studying medicine at Yale. For a group of 24...
Spring 2009
Class of 1984: 25th reunion
On Friday night, my husband, Peter Glazer (chair of therapeutic radiology, Yale), and son, Sam, and I were joined at...

Autumn 2010
New physiology chair appointed
Michael J. Caplan, M.D. ’87, Ph.D. ’87, was appointed chair of the Department of Cellular and Molecular Physiology,...
Spring 2009
Michael J. Caplan, M.D. ’87, Ph.D. ’87, FW ’89, Mark Hochstrasser, Ph.D., David J. Leffell, M.D., David A. McCormick, Ph.D., Scott A. Strobel, Ph.D.
Several faculty members have been named to endowed chairs in recent months. Michael J. Caplan, M.D. ’87, Ph.D. ’87, FW...
Winter 1999
Michael J. Caplan, M.D., Ph.D.
Michael J. Caplan, M.D., Ph.D. ’87, professor of cellular and molecular physiology, was presented the 1998 Young...

Fall/Winter 2004
In the kitchen, a way to treat cystic fibrosis?
A possible compound for the treatment of cystic fibrosis may be as close as the kitchen spice rack. Researchers at Yale...
Fall 1999 | Winter 2000
A new dean for education
One of the Ivy League’s most highly regarded medical educators is stepping down, much to the chagrin of students and...



