Richard P Lifton MD, PhD
Sterling Professor of Genetics and Professor of Medicine (Nephrology); Chair, Department of Genetics; Investigator, Howard Hughes Medical Institute
Departments & Organizations
NHLBI Proteomics
High Performance Computation
Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development: Genetics and Genomics | Biochemistry, Biophysics and Structural Biology: Cell Cycle and Signal Transduction
Kavli Institute for Neuroscience
Internal Medicine: Nephrology | Diabetes Endocrinology Research Center
Genetics
Research Interests
Molecular genetics of common human diseases more...
Education
- M.D., Stanford University, 1982
- Ph.D., Stanford University, 1986
Selected Publications
- Mani, A., et al. (2007). LRP6 mutation in a family with early coronary disease and metabolic risk factors. Science 315:1278-82.
- Ring, A.M., et al. (2007). An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis. Proc. Natl. Acad. Sci. (USA) 104:4025-9.
- Lalioti MD, Zhang J, Volkman HM, Kahle KT, Hoffmann, KE, Toka HR, Nelson-Williams C, Ellison, DH, Flavell, R, Booth, CJ, Lu Y, Geller, DS, Lifton, RP. Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule. Nature Genetics, in press.
Articles
Autumn 2009
How cells stay in shape
If you put a sponge in water it swells, and the same is true of cells. But take on too much water and a cell will...
Spring 2007
Research in Iran yields clue to heart disease
In 1998 Arya Mani, M.D., HS ’97, FW ’01, assistant professor of medicine (cardiology), returned to his native Iran to...
Autumn 2009
Genetic Diseases of the Kidney
edited by Richard P. Lifton, M.D., Ph.D., Chair and Sterling Professor of Genetics and professor of medicine, Stefan...
Winter 2003
Three join Institute of Medicine
Each year a few dozen select physicians and scientists are named to the Institute of Medicine of the National Academy...
Autumn 2011
Exome sequencing yields target gene
Yale researchers have identified genetic mutations that can trigger severe hypertension through tumor formation in the...
Autumn 2011
Yale forms partnership to develop cancer drugs
Yale and Gilead Sciences, a biopharmaceutical company based in Foster City, Calif., announced in late March that they...
Autumn 2012
Molecular profiling of tumors is cancer treatment of the future
In May 2011, Marvin B. Brooks, M.D., HS ’68, a urologist in Palm Springs, Calif., developed severe back pain while...
Winter 2010
For the first time, DNA sequencing leads to diagnosis and treatment
A Turkish boy suffering from dehydration and failure to thrive became the first patient to receive an accurate...
Spring 2012
Grant funds study of rare disorders linked to single mutant genes
While some diseases stem from a web of influences including environment, lifestyle choices, and genetic luck, others...
Winter 2002
Funding the hunt for proteins
Yale scientists have received a $15 million, five-year grant that will fund a search for key regulatory proteins in the...
Summer 2001
Three join National Academy of Sciences
Three School of Medicine faculty members were elected to the National Academy of Sciences (NAS) in May, bringing the...
Autumn 2001
New genes for hypertension
A team of Yale scientists has identified mutations in two genes that cause a rare form of hypertension. The finding has...
Winter 1999
Perfecting the Faculty Practice
David J. Leffell, M.D., medical director of the Yale Faculty Practice for the past three years and a professor of...
Winter 2003
Three professors, authorities in genetics and immunology, receive Sterling honor
Three faculty members at the School of Medicine have been named to Sterling chairs, one of the university’s highest...
Summer 1999
Richard Lifton, M.D., Ph.D.
The School of Medicine has received a $500,000 unrestricted cardiovascular/ metabolic research grant from Bristol-Myers...
Winter 2004
Margaret K. Hostetter, M.D., Richard P. Lifton, M.D., Ph.D.
Margaret K. Hostetter, M.D., chair and professor of pediatrics and professor of microbial pathogenesis, and Richard P....
Winter 2002
Richard P. Lifton, M.D., Ph.D., Pasko Rakic, M.D., Ph.D.
Richard P. Lifton, M.D., Ph.D., chair of genetics, professor of genetics, medicine and molecular biophysics and...
Spring 2007
Richard P. Lifton, Ph.D., M.D.
Richard P. Lifton, Ph.D., M.D., Sterling Professor of Genetics, chair of genetics and a Howard Hughes Medical Institute...
Spring 2008
Richard P. Lifton, M.D., Ph.D.
Richard P. Lifton, M.D., Ph.D., chair and Sterling Professor of Genetics, received the Wiley Prize in Biomedical...
Summer 1998
Richard P. Lifton, M.D., Ph.D.
Richard P. Lifton, M.D., Ph.D., professor of medicine, genetics and molecular biophysics and biochemistry, has been...
Spring 1999
Richard P. Lifton, M.D., Ph.D
Richard P. Lifton, M.D., Ph.D., chair of the Department of Genetics and professor of medicine, genetics, and molecular...
Winter 2007
Little mouse, big science
Geneticist Tian Xu has found a way to make knockout mice quickly and cheaply. By finding genes and discerning their...
Spring 2004
Journey of the heart
A collaborative bridge between Yale and Iran spanning the genetics of cardiovascular disease is a two-way street for...
Fall/Winter 2004
Getting the right fold
For almost two decades Arthur Horwich has been unraveling a basic biological mystery: how proteins achieve their native...
Winter 2003
The big move
Relocating 91 laboratories, a magnetic resonance center and the medical school’s teaching facilities across Congress...
Fall 2000 | Winter 2001
New Haven’s biotech boom
The medical school’s efforts to bring its intellectual property to market have given the New Haven economy a boost.
Autumn 2011
Is the physician-scientist an endangered species?
One of the challenges of interviewing Danny Balkin is that he keeps asking the questions—about the writing process, the...
Fall 2000 | Winter 2001
After the genome, “a new future for medicine”
The year 2000 brought the working-draft version of the human genome and new hopes for medicine and the understanding of...
Autumn 2002
“Unbreakable” bones prompt a hunt for genes
The DNA of an extended Connecticut family has yielded a possible target for the treatment and prevention of...
Fall 2000 | Winter 2001
A genetic cause for hypertension during pregnancy
Blood pressure normally dips slightly during pregnancy but, as every obstetrician knows, a spike in pressure can lead...
Fall/Winter 2004
Reunion 2004
Even as all the traditional trappings of reunion—the Friday evening clambake, the Saturday morning symposium and the...
Fall 1998
Yale scientists offer glimpse of cutting edge research
“We are in the midst of one of the great revolutions in the history of medicine,” Richard P. Lifton, M.D., Ph.D., told...
Winter 2008
Yale joins hypertension network
Two School of Medicine scientists will join colleagues in Switzerland, France and Mexico in a collaboration to pinpoint...
Summer 2001
On Student Research Day, a chance to share observations and conclusions
Three years ago, when Jacqueline C. Dolev signed up for a course to improve her clinical observation skills, she didn’t...
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