Edward Chu MD
Deputy Director, Cancer Center; Chief, Section of Medical Oncology
Departments & Organizations

Yale Medical Group
Cancer Prevention and Control Center
Developmental Therapeutics
Research Interests
Developmental therapeutics, cancer drug resistance, translational regulation, RNA-protein interactions, colorectal cancer, GI cancers, cancer drug development. more...
Education
- M.D., Brown University, 1983
Selected Publications
- Ju, J., Schmitz, J.C., Song, B., Kudo, K., and Chu, E: Regulation of p53 expression in response to 5-fluorouracil in human cancer RKO cells. Clin Cancer Res 13, 4245-4251, 2007. Schmitz, J.C., Tai, N., and Chu, E. Translational autoregulation of thymidylate synthase and dihydrofolate reductase and therapeutic implications. Frontiers in Biosciences, 2007. Chu, E. and DeVita, V.T.: Principals of Chemotherapy. In: DeVita, V.T., Lawrence, T., and Rosenberg, S.A. (Eds.), Cancer: Principles and Practice of Oncology, Eighth Edition, J.B. Lippincott Co., Philadelphia, 2008 Chu, E. and Cartwright T.H.: The pharmacoeconomic benefits of capecitabine-based chemotherapy in metastatic colorectal cancer. J Clin Oncol, 26, 2224-2226, 2008. DeVita, V.T. Jr., Chu, E.: A history of cancer chemotherapy. Cancer Res 68, 8643-8653, 2008. Saif, M.W., Choma, A., Salamone, S.J., and Chu, E.: Pharmacokinetically-guided dose adjustment of 5-fluorouracil: a rational approach to improving therapeutic outcomes. J Natl Cancer Inst, in press, 2009.
Articles

Winter 2008
Physicians’ Cancer Chemotherapy Drug Manual, 2007
by Edward Chu, M.D., professor of medicine (medical oncology) and pharmacology, and Vincent T. DeVita Jr., M.D., HS...
Winter 2008
Pocket Guide to Chemotherapy Protocols, 4th ed.
by Edward Chu, M.D., professor of medicine (medical oncology) and pharmacology (Jones & Bartlett Publishers)...
Autumn 2005
Physicians’ Cancer Chemotherapy Drug Manual 2005
by Edward Chu, M.D., professor of medicine (oncology) and pharmacology, and Vincent T. DeVita Jr., M.D., HS ’66, the...

Autumn 2006
Cancer Center moves forward after vote by New Haven Board of Aldermen
New Haven’s Board of Aldermen cleared the way for the construction of a new cancer facility

Spring 2007
New deputy director at Yale Cancer Center
Edward Chu, M.D., was named deputy director of Yale Cancer Center (YCC), effective January 1. He succeeds José Costa,...

Fall/Winter 2004
Two appointed to Cancer Center posts
Ira Mellman, Ph.D. ’78, chair and Sterling Professor of Cell Biology and professor of immunobiology, has been named...

Winter 2010
Making cancer personal
The new Smilow Cancer Hospital at Yale-New Haven is built around a new philosophy of patient care.

Autumn 2003
Building a better drug
The rational approach to drug discovery is changing pharmacology, but serendipity and imagination still play a starring...

Spring 2007
From the potion to the pill
By characterizing and quantifying the active ingredients in traditional Chinese herbal remedies, Yale scientists hope...




